Here, we discuss the case of a patient with catatonic schizophrenia treated by ECT.
Because persistent catatonia was an important element, we assessed her symptoms using the BFCRS, a gold standard scale for catatonia [20–23], and examined the relationship between s AA activity levels and BFCRS scores for catatonia before and after treatment.
A 59-year-old woman was admitted to our psychiatric department for ECT.
She had been diagnosed with schizophrenia at the age of 17 years and had taken antipsychotic drugs for 42 years.
Several studies have suggested that measuring salivary alpha-amylase activity levels is useful for evaluating the ANS activity and that s AA levels increase in schizophrenia and correlate with Brief Psychiatric Rating Scale (BPRS) scores.
However, no study has examined the relationship between s AA activity levels and symptoms of schizophrenia with catatonic state. We present the case of a 59-year-old female with persistent catatonic schizophrenia treated by electroconvulsive therapy.Besides she had been taking magnesium oxide 1.2 g and sennoside 36 mg daily for constipation for many years.The minor tranquilizer was stopped for ECT and was no longer necessary after ECT.The pathology of schizophrenia remains unknown, and a relevant biomarker remains to be identified.Various studies have been conducted to address this, including studies on the autonomic nervous system (ANS) [1–7].She exhibited severe catatonia as well as many other psychotic symptoms, such as hallucination, delusion, and negative symptoms.She was taking risperidone 9 mg daily without side effects for nearly 10 years.s AA activity levels of patients with schizophrenia have been reported to be higher than those of controls, and these levels have been associated with the severity of symptoms in patients with schizophrenia [16, 17].However, only one study has examined the change in diachronic s AA activity levels before and after treatment : it was a case report of a patient treated with electroconvulsive therapy  for schizophrenia; however, only one psychiatric symptoms rating scale, the Brief Psychiatric Rating Scale (BPRS), was used.In order to eliminate the effects of hospitalization, we measured s AA activity levels again not only immediately after hospitalization but also just before ECT.Thus, we measured her s AA activity levels twice before ECT.